Figure 5
From: Differential transcript isoform usage pre- and post-zygotic genome activation in zebrafish
Metagene projections of average H3K36me3 enrichment levels over skipped exons and surrounding introns. Metagenes based on H3K36me3 levels for upstream introns, skipped exons and downstream introns show increased H3K36me3 levels in the upstream intron and the exon, but only to minor extent in the downstream intron, as compared to background. Red line = transcripts with skipping event. Blue line = random set of introns and exons with confidence interval (light blue shaded region). The X-axis is in percentage of total length (start = 0% and end = 100%) and the Y-axis is the H3K36me3 signal normalized against input control and the total number of reads in the sample.