Functional classification of the differentially expressed genes of A. pleuropneumoniae S4074 in static and drip-flow biofilms. Bar charts represents the 4 h static biofilm (A), the 6 h static biofilm (B), the 4 h vs 6 h static biofilm experiment (C) the 28 h drip-flow biofilm (D). The white and black columns represent up-regulated and down-regulated genes, respectively. AAB, amino acid biosynthesis. BCPGC, biosynthesis of cofactors, prosthetic groups and carriers. CE, cell enveloppe. CP, cellular process. CIM, central intermediary metabolism. DM, DNA metabolism. EM, energy metabolism. FAPM, fatty acid and phospholipid metabolism. HUU, hypothetical/unclassified/unknown. MEE, mobile extrachromosomal element functions. PF, protein fate. PS, protein synthesis. PPNN, purines, pyrimidins, nucleosides and nucleotides. RF, regulatory functions. ST, signal transduction. Tr, transcription. TBP, transport and binding proteins.