Validation of the differences in mRNA expression between Fra-1+/+and Fra-1Δ/Δmice for selected microarray genes at different time points after bleomycin treatment. Lung mRNA abundance was determined by quantitative real-time RT-PCR. The graphs represent the fold change over vehicle treated Fra-1+/+ controls after normalization with the expression of GAPDH. Results are mean ± SD for 3-4 mice in each group. *p<0.05, PBS vs bleomycin; †p<0.05, Fra-1Δ/Δ vs Fra-1+/+ mice.