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Table 1 Confirmation of miRNA/mRNA expression, the miRNA-mRNA correlation and the miR-eQTLs

From: A genome-wide integrative study of microRNAs in human liver

Gene or SNP

Correlation (n = 53)

  

Q-PCR

Microarray

Replication r

Replication p

Original r

Original p

miR-148a

miR-148a

0.48

0.001

-

-

miR-185a

miR-185a

0.52

0.0003

-

-

PTGIS

PTGIS

0.5

0.0002

-

-

ADRB2

ADRB2

0.94

<1 × 10-7

-

-

miR-148a vs PTGIS

 

−0.36

0.016

−0.36

0.012

miR-185a vs ADRB2

 

−0.43

0.003

−0.46

0.001

miR-185a vs rs1220

 

0.32

0.029

0.39

0.006

  1. The correlation coefficient (r) and statistical significance (p) of the comparisons between Q-PCR data and the original microarray data are shown. Analyses were based on the samples for which RNA was available (n = 53).
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BMC Genomics

ISSN: 1471-2164

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