ISWI maintains tDNA chromatin. Heat maps in A) and B) compare the nucleosomes on 112 genes, which show nucleosome changes in isw1∆2∆ cells compared to wild type cells. C) Comparison of average nucleosome occupancy profiles under two conditions as in panels A and B. D) Isw1 and Isw2 occupy different regions on yeast tDNAs [13, 26]. E) Venn intersections among Isw1 target genes and the genes that show nucleosome gain on gene body either in isw1∆ or isw1∆2∆ cells.