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Table 1 Highly splicing-regulated and highly repressive MRE regions in VEGF gene

From: Fine-tuning of microRNA-mediated repression of mRNA by splicing-regulated and highly repressive microRNA recognition element

Region MRE region microRNA$ Range of repressive ratio (%) Supported tissue from Fisher’s exact test
Start End Cancer Normal
Left side Right side Two tail Left side Right side Two tail
1 1742 1782 hsa-miR-125a(15), hsa-miR-140(48) 15 ~ 48 Thyroid   Thyroid    
2 1899 1921 hsa-miR-17-5p(35), hsa-miR-20a(39), hsa-miR-20b(41), hsa-miR-106a(21), hsa-miR-106b(35), has-miR-302d(30), hsa-miR-372(30), hsa-miR-520 g(19), hsa-miR-520 h(28) 19 ~ 41       
3 1935 1955 hsa-miR-302d(40) 30   Ovary Ovary    
4 1992 2020 hsa-miR-15a(50), hsa-miR-16(51), hsa-miR-195(45) 45 ~ 51       
5 2221 2243 hsa-miR-150(30) 30       
6 2258 2282 hsa-miR-205(13) 13       
7 2508 2554 hsa-miR-15b(25), hsa-miR-107(42), hsa-miR-147(39), hsa-miR-330(25)* 25 ~ 42   Salivary gland Salivary gland   Liver Liver
8 2567 2601 hsa-miR-34a(15), hsa-miR-34b(8), hsa-miR-373(22), hsa-miR-378(17) 8 ~ 22       
9 3009 3029 hsa-miR-504(30) 30 Brain   Brain    
10 3134 3160 hsa-miR-383(25) 25       
11 3151 3172 hsa-miR-134(45) 45      Pancreatic islet Pancreatic islet
12 3342 3362 hsa-miR-361(45) 45       
13 3466 3486 hsa-miR-29b(18) 18       
  1. $ Number in parentheses showed the experimental result of repressive ratio [48]. * The repressive ratio of hsa-miR-330 is inconsistent from original results.