Table 3 Selected DAVID results of the 56 human orthologs of genes with a significant effect for significantly different levels of transcript abundance between arteries in both age groups
| Â | Term | Description | Count | FDR | Genes |
|---|---|---|---|---|---|
GO cell component | GO:0005576 | extracellular region | 12 | 0.9679 | CD97, SCUBE3, NPNT, PAMR1, CST3, KITLG, NID1, THBS1, GDNF, CCL28, RNPEP, CR1L |
GO:0005856 | cytoskeleton | 9 | 0.9194 | FAM65B, DBNL, SORBS2, TPPP, OPHN1, KITLG, FKBP15, FARP1, ITPR1 | |
GO biological process | GO:0022610 | biological adhesion | 7 | 0.8785 | CD97, NPNT, KITLG, NID1, SCARB2, THBS1, NPHP1 |
GO:0006955 | immune response | 6 | 0.9087 | CD97, TRAF3IP2, DBNL, MYD88, THBS1, CCL28 | |
GO:0043405 | regulation of MAP kinase activity | 3 | 0.92 | DBNL, KITLG, THBS1 | |
GO molecular function | GO:0005509 | calcium ion binding | 7 | 0.9999 | CD97, SCUBE3, NPNT, CBL, NID1, THBS1, ITPR1 |
GO:0008092 | cytoskeletal protein binding | 5 | 0.9968 | DBNL, SORBS2, TPPP, OPHN1, FARP1 | |
GO:0050840 | extracellular matrix binding | 2 | 0.9915 | NID1, THBS1 | |
KEGG pathway | hsa04270 | Vascular smooth muscle contraction | 4 | 0.1137 | ADRA1B, PPP1R12A, PPP1R14A, ITPR1 |
hsa04020 | Calcium signaling pathway | 3 | 0.8054 | PLN, ADRA1B, ITPR1 |