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Table 3 Details of single nucleotide polymorphisms (SNPs) detected within the 454 data

From: Next generation sequencing of viral RNA genomes

Virus Average depth Maximum depth Depth at SNP % variant Position (genome) Gene (Position) Nuc cons Nuc variant AA cons AA variant AA residue
Brain tissue samples      
RV437 44 103 60 8 2768 M (275) T C Leu Ser 92
63 3 2781 M (288) T C Val Val 96
55 51 3049 M (556) T C Leu Phe 186
28 18 4403 G (1090) T C Leu Leu 364
28 7 7855 L (2451) C T Asn Asn 817
RV2417 35.5 81 NA         
RV61 53.2 165 34 18 3503 G (209) C T Ile Thr 70
RV2508 17 53 17 23 9523 L (4128) A G Ser Ser 1376
RV2627 17.7 46 NA         
RV2516 16.5 43 NA         
RV50 8.6 16 11 27 11349 L (5944) C G Asn Asp 1982
RV2772 14.5 31 13 38 1293 N (1223) A G Lys Arg 408
22 5 8179 L (2771) T A Phe Tyr 924
Cultured virus samples      
RV2324 65 272 47 11 3490 G (175) G A Glu Lys 59
47 21 3491 G (176) A G Glu Gly 59
42 31 3711 G (396) C A His Gln 132
44 25 4103 G (788) A G Gln Arg 263
36 11 8376 L (2967) C T Asp Asp 989
RV1787 combined 4.3 11 4 25 2679 M (170) G A Gly Glu 57
RV20 combined 156 277 107 2 346 N (276) C A/T Tyr */Tyr 92
87 2 1621 P (105) T C Ser Ser 35
81 2 1669 P (153) G A Glu Glu 51
77 3 1710 P (194) A T Gln Leu 65
93 39 3143 M-G (NA) C T NA NA NA
103 2 3671 G (356) G A Trp * 119
96 2 4403 G (1087) T C Cys Arg 363
94 37 4584 G (1268) T C Met Thr 423
95 2 6217 L (766) T C Ser Pro 256
134 1 7910 L (2459) T C Ile Thr 820
107 2 8244 L (2793) C A Ser Arg 931
    106 2 8473 L (3022) A G Thr Ala 1008
  1. NA = not applicable as no SNPs were observed. * stop codon.