Figure 1

Genomic organization of α-tubulin genes and surrounding regions in three Leishmania species. Panel A: comparison among L. braziliensis (LbrM) α-tubulin loci and syntenic regions in L. infantum (LinJ) and L. major (LmjF) genomes. Panel B: comparison among the specific L. infantum α-tubulin locus and the syntenic regions of L. braziliensis and L. major, species in which this locus is absent. Red boxes represent the α-tubulin genes. L. major α-tubulin locus contains 12 genes (dashed rectangle). Each block of syntenic genes in the different Leishmania species, and reorganization events affecting them, is colored differently. The diagonal arrow, point to the LinJ.13.1560 that has an inverted orientation regarding the homologous gene in L. major (B). Blue vertical bars denote gaps in sequence. Numbers in bold at the start and end of each gene cluster are the last four digits of GeneDB gene entries.