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Table 2 The most significant changes in expression of genes from the HSPs family (and some other chaperones)

From: Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

Entrez gene ID

Mean SC_C

Mean SC_38

SLR SC_38 vs C

Mean HEP_C

Mean HEP_43

SLR HEP_43 vs C

Gene symbol (full name)

1100037258

7.01

5.48

−1.53

9.34

9.13

−0.22

Dnajc3 (DnaJ (Hsp40) homolog, subfamily C, member 3)

12330

8.69

7.54

−1.15

10.29

10.07

−0.22

Canx (calnexin)

15502

9.50

8.41

−1.09

11.65

12.72

1.07

Dnaja1 (DnaJ (Hsp40) homolog, subfamily B, member 1)

22027

10.93

9.90

−1.03

11.78

11.63

−0.15

Hsp90b1 (heat shock protein 90, beta (Grp94), member 1)

224273

9.90

8.87

−1.02

5.95

5.92

−0.03

Crybg3 (beta-gamma crystallin domain containing 3)

14231

7.16

8.75

1.59

5.51

5.61

0.10

Fkbp7 (FK506 binding protein 7)

53380

6.92

8.25

1.33

6.83

6.77

−0.06

Psmd10 (proteasome (prosome, ma-cropain) 26S subunit, non-ATPase, 10)

70430

6.94

8.07

1.12

6.87

6.96

0.09

Tbce (tubulin-specific chaperone E)

193740

5.86

6.46

0.59

6.93

13.10

6.17

Hspa1a (heat shock protein 1A)

81489

11.40

10.78

−0.62

8.48

12.88

4.40

Dnajb1 (DnaJ (Hsp40) homolog, subfamily B, member 1)

58233

8.23

8.79

0.56

6.18

9.98

3.80

Dnaja4 (DnaJ (Hsp40) homolog, subfamily A, member 4)

15511

4.96

5.03

0.07

9.55

13.22

3.67

Hspa1b (heat shock protein 1B)

15505

7.77

7.64

−0.13

9.18

11.65

2.47

Hsph1 (heat shock 105kDa/110kDa protein 1)

80888

5.09

5.32

0.23

10.16

11.73

1.58

Hspb8 (heat shock protein 8)

67035

10.05

10.21

0.16

8.83

10.19

1.36

Dnajb4 (DnaJ (Hsp40) homolog, subfamily B, member 4)

12406

5.78

6.21

0.43

6.36

7.72

1.36

Serpinh1 (serine (or cysteine) peptidase inhibitor, clade H, member 1)

15516

9.94

9.35

−0.59

11.29

12.31

1.02

Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1)

15528

7.03

7.09

0.06

8.63

9.64

1.01

Hspe1 (heat shock protein 1 (chaperonin 10))

  1. The level of expression in spermatocytes (SC) and in hepatocytes (HEP) is given in arbitrary units in logarithmic scale (log2). Changes in gene expression following heat shock (at 38°C or 43°C) are shown as SLRs.