Table 1 Number of differentially methylated probes sorted by genomic region
All probes | Probes located within 1500 bp upstream, 5'UTR and 1st Exon (“non‒gene body” probes) | 5'UTR and 1st Exon (“non‒gene body” probes) Transcription Start Site (Excludes 5’UTR/1st Exon) | ||||||
|---|---|---|---|---|---|---|---|---|
Quadrant number Additional file 1: Figure S4) | Probe Count | Proportion to total probes in group | Probe Count | Proportion to total probes in group | Proportion to all analysable probes | Probe Count | Proportion to total probes in group | Proportion to all analysable probes |
351952 | 100.00% | 184099 | 100.00% | 52.31% | 130656 | 100.00% | 37.12% | |
Q1 | 866 | 0.25% | 462 | 0.35% | 0.13% | 292 | 0.22% | 0.08% |
Q2 | 3441 | 0.98% | 955 | 0.73% | 0.27% | 619 | 0.47% | 0.18% |
Q3 | 2388 | 0.68% | 1011 | 0.77% | 0.29% | 627 | 0.48% | 0.18% |
Q4 | 711 | 0.20% | 301 | 0.23% | 0.09% | 179 | 0.14% | 0.05% |
Probes on Enhancer Regions | Promoter Associated Probes | Gene Body Only (not 5’UTR or 1st Exon) | ||||||
Probe Count | Proportion to total probes in group | Proportion to all analysable probes | Probe Count | Proportion to total probes in group | Proportion to all analysable probes | Probe Count | Proportion to total probes in group | Proportion to all analysable probes |
59317 | 100.00% | 16.85% | 91601 | 100.00% | 26.03% | 146423 | 100.00% | 41.60% |
275 | 0.46% | 0.08% | 97 | 0.11% | 0.03% | 359 | 0.25% | 0.10% |
1239 | 2.09% | 0.35% | 145 | 0.16% | 0.04% | 2220 | 1.52% | 0.63% |
960 | 1.62% | 0.27% | 214 | 0.23% | 0.06% | 1221 | 0.83% | 0.63% |
286 | 0.48% | 0.08% | 65 | 0.07% | 0.02% | 379 | 0.26% | 0.11% |