Table 1 The maximum absolute difference in power (over the type-1 error rate) between weighting and collapsing pooling strategies for different tests and phenotype scenarios in population genetics simulations
From: Comparison of similarity-based tests and pooling strategies for rare variants
Scenario/Test | MDMR | SKAT | KBAT | U-Test |
|---|---|---|---|---|
Risk Rare | 0.466 | 0.472 | 0.157 | 0.511 |
Risk Both | 0.395 | 0.29 | 0.094 | 0.379 |
Risk Common | 0.551 | 0.479 | 0.388 | 0.235 |
Mixed Rare | 0.18 | 0.516 | 0.393 | 0.148 |