Figure 3

Data supporting identification of a G-box-binding ApiAP2 and G-box-like motifs. A. Binding motif for ApiAP2 domain Cgd8_810 as determined by protein-binding microarray. Cgd8_810 expression data for 2, 6, 12, 24, 36, 48 and 72 hours post-infection are indicated. B. Identified G-box-like motifs overrepresented in cluster upstream regions. Motif name and total number of genes possessing each motif per total genes in all clusters where the motif is overrepresented are indicated. C. Expression data for all genes from each cluster where the motif is overrepresented. Each row indicates a gene; rows are sorted first by cluster, then by peak expression at each time point. Gene IDs for genes associated with each cluster can be found in Additional file 1: Table S2. Expression is indicated on a scale of 0-100% of max for each gene. D. Six representative cluster profiles selected from the 54 clusters containing overrepresented G-box-like motifs. Line colors for individual gene profiles indicate the membership values of that gene profile to the cluster ranging from 0.5 to 1. Each cluster profile is located next to the corresponding rows in the gene expression heatmap. E. Cluster number and total number of genes in each displayed representative cluster.