Figure 2From: Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epitheliaComparison of the hypothesis-led and hypothesis-free approaches. The former seeks to identify genes underlying processes demonstrated experimentally, or predicted, in the literature. The latter is based on co-expression or enrichment in tissues of interest compared with other tissues, or the whole organism. Although both identify genes of interest that underly known functions, the hypothesis-free approach also identifies co-enriched genes without prior knowledge, potentially leading to unexpected research hypotheses.Back to article page