Table 3 Numbers of reads per million mapping to known canine MHC genes, summarised for the various tissues plus the combined assembly (see Methods for details)
Class | Gene | Reference | Chromosome in dog | Tissue | Combined | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Heart | Intestine | Kidney | Lung | Skin | Spleen | Testis | |||||
I | DLA-64 | ENSCAFG00000000500 | 12 | 78.4 | 257.1 | 324.8 | 390.2 | 85.2 | 687.6 | 61.5 | 240.7 |
I | DLA-79 | ENSCAFG00000008234 | 18 | 0.0 | 0.0 | 14.9 | 0.0 | 15.6 | 3.6 | 0.0 | 10.5 |
I | DLA-88 Precursor | ENSCAFG00000000487 | 12 | 0.0 | 269.1 | 268.2 | 451.5 | 43.6 | 654.8 | 61.5 | 210.3 |
I | DLA-88 | ENSCAFG00000000492 | 12 | 78.4 | 191.4 | 283.1 | 550.9 | 1.0 | 753.0 | 71.7 | 207.8 |
I | Tapasin | ENSCAFG00000000972 | 12 | 0.0 | 41.9 | 110.2 | 91.8 | 2.1 | 149.2 | 30.7 | 50.8 |
II | BTNL2 | ENSCAFG00000000797 | 12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
II | CD74 | ENSCAFG00000018101 | 4 | 52.3 | 71.8 | 143.0 | 145.4 | 0.0 | 338.3 | 41.0 | 88.7 |
II | DLA-DRA | ENSCAFG00000000803 | 12 | 26.1 | 59.8 | 134.1 | 298.4 | 165.2 | 516.6 | 20.5 | 198.3 |
II | DQ Alpha precursor | ENSCAFG00000000812 | 12 | 0.0 | 6.0 | 65.6 | 168.3 | 83.1 | 247.4 | 10.2 | 96.7 |
II | HLA-DMA | ENSCAFG00000000848 | 12 | 0.0 | 0.0 | 3.0 | 0.0 | 1.0 | 7.3 | 0.0 | 2.0 |
II | HLA-DOA | ENSCAFG00000000896 | 12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 3.6 | 20.5 | 1.5 |
II | HLA-DOB | ENSCAFG00000000819 | 12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
II | HLA-DPB1 | ENSCAFG00000000900 | 12 | 0.0 | 0.0 | 3.0 | 0.0 | 3.1 | 0.0 | 0.0 | 2.0 |
II | HLA-DQB1 | ENSCAFG00000000814 | 12 | 0.0 | 17.9 | 26.8 | 53.6 | 6.2 | 54.6 | 10.2 | 20.4 |
II | HLA-DRB1 | ENSCAFG00000000806 | 12 | 52.3 | 59.8 | 83.4 | 336.7 | 40.5 | 232.8 | 51.2 | 95.7 |
II | IK cytokine | ENSCAFG00000005869 | 2 | 52.3 | 6.0 | 62.6 | 38.3 | 128.9 | 36.4 | 61.5 | 84.2 |
II | RFX3 | ENSCAFG00000002053 | 1 | 0.0 | 47.8 | 8.9 | 0.0 | 0.0 | 0.0 | 61.5 | 8.5 |
III | BAG6 | ENSCAFG00000000575 | 12 | 130.7 | 131.6 | 122.2 | 122.4 | 4.2 | 80.0 | 706.9 | 89.2 |
III | HSP70 | ENSCAFG00000000641 | 12 | 2117.7 | 998.7 | 2413.4 | 7789.6 | 83.1 | 4565.6 | 624.9 | 1730.3 |
III | LTA | ENSCAFG00000000515 | 12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
III | TNF | ENSCAFG00000000517 | 12 | 0.0 | 0.0 | 0.0 | 7.7 | 0.0 | 0.0 | 0.0 | 0.5 |
| Â | Â | Â | Total class I | 156.9 | 759.5 | 1001.1 | 1484.5 | 147.6 | 2248.2 | 225.4 | 720.1 |
| Â | Â | Â | Total class II | 183.0 | 269.1 | 530.4 | 1040.7 | 428.1 | 1437.0 | 276.6 | 598.0 |
| Â | Â | Â | Total class III | 2248.4 | 1130.2 | 2535.6 | 7919.7 | 87.3 | 4645.6 | 1331.9 | 1820.0 |
| Â | Â | Â | Grand total | 2588.3 | 2158.8 | 4067.1 | 10444.8 | 663.0 | 8330.8 | 1833.9 | 3138.1 |