Figure 3
From: Genome-wide analysis of H4K5 acetylation associated with fear memory in mice
Qualitative assessment of H4K5ac and gene expression. (A) Expressed genes in the adult mouse hippocampus 1 hour after CFC compared to naïve controls are ranked from the lowest (cyan) to the highest expressed (orange) into 10 equal bins (1801 genes). Genes ranked by expression are correlated to average coverage for H4K5ac in (B) FC and (C) control mice re-exposed to the context on day 3, or to (D) H4K12ac immediately after CFC on day 1; average read coverage ± 5 kb relative to the TSS. (E) Venn diagram of unique and overlapping genes identified by acetylation above the average across all genes: with an H4K5ac threshold of greater than 50 reads in promoter, and a threshold of greater than 10 reads in promoter for H4K12ac.