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Figure 11 | BMC Genomics

Figure 11

From: Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum

Figure 11

METH produces increased expression and increased H4K5Ac binding in a small number of genes in METH-pretreated rats. (A). METH increased gene expression and H4K5Ac binding in TSSs of genes involved in molecular transport and in carbohydrate and lipid metabolism. Quantitative PCR was used to validate the results of the microarray (B) and ChIP-Seq (C) analyses. Statistical analyses are described in the text. *, **, *** = p < 0.05, 0.001, 0.001, respectively, in comparison to the SS group; #, ##, ### = p < 0.05, 0.01, 0.001, respectively in comparison to the SM group; !, !!, !!! = p < 0.05, 0.01, 0.001, respectively in comparison to the MS group.

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BMC Genomics

ISSN: 1471-2164

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