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Table 2 Effects of acute METH injection on gene expression and H4K5Ac binding in METH-pretreated rats

From: Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum

Symbol

Definition

FC

Binding

Olr577

Olfactory receptor 577

6.39

*

Npb

Neuropeptide B

5.70

4.22

Plagl2

Pleiomorphic adenoma gene-like 2

4.67

*

Cpt1b

Carnitine palmitoyltransferase 1b, muscle

3.91

*

Ppef2

Protein phosphatase, EF hand calcium-binding domain

3.07

2.95

Gpr143

G protein-coupled receptor 143 (Gpr143), mRNA.

2.88

4.88

Nr4a3

Nuclear receptor subfamily 4, group A, member 3

2.79

4.22

Foxa3

Forkhead box A3

2.60

NC

Olr734

Olfactory receptor 734

2.28

*

Olfml2a

Olfactomedin-like 2A

−1.71

NC

Zfp533

Zinc finger protein 533

−1.73

*

Pard3

Par-3 (partitioning defective 3) homolog (C. elegans)

−1.74

−3.94

Tle4

Transducin-like enhancer of split 4, homolog of Drosophila E [20]

−1.75

−4.22

Bcar3

Breast cancer anti-estrogen resistance 3

−1.76

−2.94

Plag1

Pleiomorphic adenoma gene 1

−1.76

*

Rcn1

Reticulocalbin 1

−1.81

*

Gpcr12

G-protein coupled receptor 12

−1.81

NC

Arl6

ADP-ribosylation factor-like 6

−1.87

NC

Prkcm

Protein kinase C, mu

−1.88

*

Clcn1

Chloride channel 1

−1.90

*

Jag1

Jagged 1

−1.94

−3.50

Fbxo15

F-box protein 15

−1.96

*

Bmp2

Bone morphogenetic protein 2

−1.99

−3.14

Cd44

CD44 antigen

−2.01

*

Rims2

Regulating synaptic membrane exocytosis 2

−2.13

−3.50

Gpr149

G protein-coupled receptor 149

−2.14

−3.23

Spdya

Speedy homolog A (Drosophila)

−2.35

NC

Plin

Perilipin

−2.47

*

Stag3

Stromal antigen 3

−2.51

*

Clca3

Chloride channel calcium activated 3

−3.77

*

Cldn22

Claudin 22

−3.89

NC

Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

−4.36

NC

Olr990

Olfactory receptor 990

−4.50

*

Ctcfl

CCCTC-binding factor (zinc finger protein)-like

−5.45

*

Sdfr2

Stromal cell derived factor receptor 2

−6.02

*

Traf4af1

TRAF4 associated factor 1

−8.83

NC

Plg

Plasminogen

−9.93

*

  1. Genes were identified and calculations were performed as described in Table 1. Abbreviations: FC fold changes, NC no changes in H4K5Ac binding, *, no H4K5Ac binding sites observed.