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Table 1 Observed V(D)J recombination events

From: Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies

 

V-D-J

V-J

D-J

V-D

V-V

t(X;X)

Sample

      

A) pre-B ALL

 

(1) IGH*

    

(1) IGK

MCL

 

(2) IGL

(1) IGH

   

RAMOS

 

(1) IGK

(1) IGH

   

B) chronic T-Cell leukemia

 

(1) TRB

    

DB

    

(1) IGH

t(14;18)

ARH-77

    

(1) IGH

 

C)  LCL

 

(2) IGK

(5) IGH

(1) IGH

(1) IGH

 

(1) IGK

Loucy

(2) TRB

  

(1) IGH

  

Burkitt-like lymphoma

 

(1) IGK

   

t(2;8)

  1. (A) Samples for which only canonical V-D-J recombination was observed. *The V-J rearrangement observed in the pre-B ALL is likely to be normal V-D-J, however we obtained full read alignments only for read pairs mapping one end to IGHJ4 and the other to IGHV4-34. (B) Samples for which only non-canonical events were observed. Non-canonical events are indicated as italicized text. (C) Samples for which both canonical and non-canonical events were observed.
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BMC Genomics

ISSN: 1471-2164

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