Figure 3
From: Molecular signatures of mammalian hibernation: comparisons with alternative phenotypes
Patterns of gene expression in ischemia-reperfusion (CN-IS-RP) and hibernation (P-T-A). The expression values were normalized to (-1,1) in the ischemia-reperfusion (A) and hibernation datasets (B). Gene expression trends were clustered into nine patterns by self-organizing mapping. The numbers of genes in each pattern are shown on the top of the grids. The patterns that contain the most genes are in the top left and bottom right of each map. One of the major patterns shared between ischemia-reperfusion and hibernation is the high-low-low pattern (A and B, top left). One major difference between ischemia-reperfusion and hibernation is that hibernation exhibits a low-high-high pattern (B, right bottom). CN: control; IS: ischemia; RP: reperfusion; T: torpor; A: arousal episodes; P: post-reproduction.