Figure 5
From: Molecular signatures of mammalian hibernation: comparisons with alternative phenotypes
Comparison of molecular signatures during hibernation to non-hibernation physiological conditions. (A) The most significant molecular signatures during hibernation in comparison with calorie restriction, PPARα knockout, sleep deprivation, and cold exposure. (B) Highlighted genes exhibited reasonable changes in direction in physiological conditions and hibernation (opposite in PPARα knockout and T vs. P, opposite in sleep deprivation and T vs. A, consistent in calorie restriction and hibernation signatures, consistent in cold exposure and hypothermia signatures). The arc lines divide the different hibernation signatures (T vs. P, T vs. A, and A vs. P). The color of the gene indicates the condition it belongs to. Genes with multiple colors are differentially expressed in more than one physiological condition. The gene sizes were scaled to log2 fold-changes of genes in hibernation. T: torpor; A: arousal episodes; P: post-reproduction.