Table 1 Selected differentially regulated genes in the parS and parR mutants compared to WT

Down-regulated genes

PA2491

mexS

−3.51

−2.39

Oxidoreductase

PA2493

mexE

−8.21

−7.30

Multidrug efflux membrane fusion protein

PA2494

mexF

−8.75

−9.36

Multidrug efflux transporter

PA2495

oprN

−7.11

−8.53

Multidrug efflux outer membrane protein

PA2811

…

−2.05

−0.45

Probable permease of ABC transporter

PA2812

…

−2.62

−0.86

Probable ABC transporter

PA2813

…

−2.44

−1.36

Probable glutathione S-transferase

PA3229

…

−7.4

−5.2

Hypothetical protein

PA4354

…

−3.07

−1.47

Conserved hypothetical protein

PA4356

…

−3.55

−2.94

Xenobiotic reductase

PA4623

…

−4.55

−4.91

Hypothetical protein

PA4661

pagL

−1.01

−0.72

Lipid A 3-O-deacylase

PA4881

…

−10.68

−9.13

Hypothetical protein

Up-regulated genes

PA0051

phzH

3.56

1.40

Phenazine-modifying enzyme

PA0441

…

1.86

1.53

Dihydropyrimidinase

PA0523

norC

3.61

2.52

Nitric-oxide reductase subunit C

PA0524

norB

3.24

1.84

Nitric-oxide reductase subunit B

PA0525

norD

2.56

1.32

Probable dinitrification protein D

PA1130

rhlC

3.07

2.42

Rhamnosyltransferase 2

PA1671

stk1

2.78

2.99

Serine-threonine kinase

PA1707

pcrH

2.09

2.23

Regulatory protein

PA1778

cobA

1.92

2.14

Methyltransferase

PA2193

hcnA

3.86

5.95

Hydrogen cyanide synthase

PA2300

chiC

5.52

2.27

Chitinase

PA2303

ambD

0.92

1.53

Taurine catabolism dioxygenase

PA1899

phzA2

12.66

11.33

Phenazine biosynthesis protein

PA1900

phzB2

5.26

1.79

Phenazine biosynthesis protein

PA2593

qteE

3.18

2.53

Quorum threshold expression element

PA3326

clpP2

2.80

3.33

Protease

PA3331

…

5.82

5.56

Cytochrome P450

PA3333

fabH2

6.82

6.36

3-oxoacyl-[acyl-carrier-protein] synthase III

PA3478

rhlB

3.68

2.50

Rhamnosyltransferase chain B

PA3479

rhlA

4.37

3.31

Rhamnosyltransferase chain A

PA3724

lasB

4.29

3.32

Elastase

PA3757

nagR

1.75

3.48

Transcriptional regulator

PA3974

ladS

1.52

1.40

Sensor protein

PA4133

…

4.07

4.47

Cytochrome C oxidase subunit

PA4209

phzM

4.22

1.94

Phenazine-specific methyltransferase

PA4211

phzB1

5.72

8.13

Phenazine biosynthesis protein

PA4217

phzS

6.04

5.95

Flavin-containing monooxygenase