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Figure 4 | BMC Genomics

Figure 4

From: miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells

Figure 4

Modulation of miR-296-3p and miR-298-5p alters expression of their targets. Bar graph showing changes in gene expression of a selected set of miR-296-3p and miR-298-5p targets for each of three different experimental conditions: (i) αTC1-6 treated with cytokines with respect to matched untreated control cells at the time points 24 and 48 h; (ii) untreated αTC1-6 transfected with mimics of miR-296-3p with respect to scramble-transfected control cells at the time points 24 and 48 h; (iii) untreated αTC1-6 transfected with mimics of miR-298-5p with respect to scramble-transfected control cells at the time points 24 and 48 h. Data are reported as LOG of 2^-ΔΔCt values. Hprt and Ppia were used as endogenous controls to normalize real-time PCR data.

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BMC Genomics

ISSN: 1471-2164

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