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Table 2 Genes differentially expressed by ArcA under aerobic conditions with or without H 2 O 2 that have predicted ArcA binding sites

From: Probing the ArcA regulon under aerobic/ROS conditions in Salmonella enterica serovar Typhimurium

Gene ID

Gene ID

Gene name

Fold change H2O2/control

Fold change control

Strand

PositionA

Sequence

p-valueB

Function

LT2

14028s

 

14028s

ΔarcA

ΔarcA/14028s

  

5′ - 3′

  

STM0958

STM14_1080.J

trxB

4.93

1.9

1.35

-

94

GTTAACAATATGTGT

1.00E-05

thioredoxin reductase

+

85

GTTAACAAAATCGTT

5.70E-05

STM1520

STM14_1838

marR

1.75

−1.38

−1.02

-

73

GTCAACTAAATGAAT

9.50E-05

DNA-binding transcriptional repressor MarR

STM1586

STM14_1918

-

5.55

2.75

1.06

+

171

GTTAAGAAAATGTGC

9.50E-05

putative periplasmic protein

STM3216

STM14_3893

tsr

1.17

−1.65

−1.31

-

198

GTTAACCATTTCTTA

8.10E-06

putative methyl-accepting chemotaxis protein

STM2445

STM14_3003

ucpA

−5.34

−1.83

−1.86

+

44

GTTAATGGAGTGTAA

1.20E-05

short chain dehydrogenase

STM1795

STM14_2170

gluD

−6.28

−1.34

−1.94

-

121

GTTAACTATCCGCTA

9.50E-05

putative glutamic dehyrogenase-like protein

STM4087

STM14_4913

glpF

−1.63

−5.7

8.77

+

217

GTTAATGAAATGATT

1.00E-05

glycerol diffusion

STM1771

STM14_2141

chaA

−1.77

−5.97

3.31

-

36

GTTAATATTTTGGAA

8.00E-05

calcium/sodium:proton antiporter

STM1125

STM14_1281

putP

−8.81

−3.4

−3.46

+

234

GTTAACACTTTTAAA

9.50E-05

major sodium/proline symporter

STM1091

STM14_1237

sopB

−2.17

−3.57

−5.89

+

52

GTTAACCCTGTTGAA

8.00E-05

secreted effector protein

STM2866

STM14_3463

sprB

−6.06

−2.32

−3.51

+

281

GTTAATGAAAGGGAA

8.10E-06

transcriptional regulator

STM4405

STM14_5290

ytfJ

−3.2

−1.45

−2.31

-

67

GTTAATCATATGTGC

3.30E-05

putative transcriptional regulator

STM4535

STM14_5449

-

−2.7

−1.04

−2.76

-

98

GTTAACAGAGGGAAA

9.50E-05

putative PTS permease

STM4467

STM14_5361

 

−1.83

1.02

−2.07

-

271

GTTAATTATTTGTTT

6.50E-06

arginine deiminase

STM1130

STM14_1293

nanM

−2.58

1.01

−2.92

+

115

GATAACTCCATGTAA

8.00E-05

putative inner membrane protein

STM4165

STM14_5006

rsd

2.75

1.69

2.74

-

67

GTTAACAACATGCCA

1.20E-05

anti-RNA polymerase sigma 70 factor

STM1728

STM14_2091

yciG

1.68

1.95

−2.11

-

261

GTTAATGCATTGTTT

1.50E-05

putative cytoplasmic protein

STM0292

STM14_0341

-

1.18

2.12

2.18

-

248

GTTCATCAAATGTAG

6.80E-05

putative RHS-like protein

STM2220

STM14_2744

yejG

5.84

2.41

2.94

+

64

GTCAATGATGTGTTA

6.80E-05

hypothetical protein

STM1770

STM14_2140

chaB

2.07

3.64

−2.12

+

245

GTTAATATTTTGGAA

8.00E-05

cation transport regulator

STM1211

STM14_1385.J

ndh

7.09

3.58

2.24

-

44

GTTAATTAAAAGTTA

1.10E-06

respiratory NADH dehydrogenase 2

+

65

GTTAATTAAAGGCTA

1.00E-05

-

33

ATTAACCAATTGTTA

9.50E-05

STM1746.S

STM14_2110

oppA

−7.87

−2.46

−3.08

+

318

GTTAACAAAATTGTA

1.00E-05

oligopeptide transport protein

-

327

GTTAACCAATTCTCT

6.80E-05

STM1818

STM14_2199

fadD

−1.56

−1.85

2.56

+

75

GTTAATATAATGTTA

1.00E-05

long-chain-fatty-acid--CoA ligase

+

64

GTTAACGACTTGTTT

1.00E-05

STM3692

STM14_4451

lldP

−13.27

−2.11

−6.83

-

125

GTTAACCAGATGTTA

2.00E-06

L-lactate permease

+

136

GTTAACTATTTGTTG

5.20E-06

-

173

GTTAATTTAATGAAA

1.90E-05

STM1303

STM14_1582

argD

−2.63

−1.11

−2.95

-

40

GTTATTTATATGTTA

2.80E-05

bifunctional succinylornithine transaminase

+

112

GTTTATGCAATGTTA

5.70E-05

  1. Alocation of the binding sequence is in bp upstream of the translation start site in the genome of S. Typhimurium 14028s [37].
  2. Bp-value estimates the significance of the weight associated to each site [38].