Figure 3

Representation of NRPS sequences of strains BAI3 and X11-5A of X. oryzae pv. oryzae. A. Representation of the NRPS locus META-B of X. oryzae pv. oryzae strain BAI3. B. Representation of contigs of X. oryzae pv. oryzae strain X11-5A that contain a nucleotide sequence encoding at least one A domain and/or a nucleotide sequence encoding non-NRPS genes similar to genes found in the locus META-B of strain X. albilineans GPE PC73. ???? : undetermined sequence located between contigs. Two contigs separated by this tag may be located in two different genomic regions (they are not necessarily contiguous). Brown arrows: staM and staM’ genes predicted to be required for β-hydroxylation of two unidentified amino acids, respectively. Purple arrow: daT gene predicted to be required for biosynthesis of Dab (2,4-diamino butyric acid). Orange arrows: genes predicted to be required for biosynthesis of Dpg (3,5-dihydroxyphenyl-glycine). Dark blue arrows: other genes conserved in all META-B loci (ABC transporter, MbtH-like protein and transcriptional regulator AraC). Green arrows and yellow arrow: genes conserved in strains X11-5A and XaS3 predicted to be required for biosynthesis of an unknown non-proteinogenic amino acid (Hp: hypothetical protein gene, TA: transaminase gene, DH: lactate dehydrogenase gene). Light blue arrow: syrP gene predicted to be required for β-hydroxylation of an unknown amino acid. Black arrows: NRPS genes. Length of arrows is not proportional to the length of genes. All information regarding characteristics and color-code for NRPS modules are as detailed in Figure 2. IS: insertion sequence. FS: frameshift mutation. Dotted box or dotted arrow: pseudogene. Dotted circle: non-functional module.