Figure 4
From: Intronic Non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees
Non-CpG methylation is enriched in splice junctions. a, In AHB, over 97% of splice donors that are methylated on the template strand have the sequence GU (i.e., 209/216 have the template sequence AmC) and over 98% of splice acceptors that are methylated on the template strand have the sequence AG (i.e., 128/130 have the template sequence mCT). Similarly in EHB, over 99% of splice donors that are methylated on the template strand have the sequence GU (i.e., 877/885 have the template sequence AmC) and over 99% of splice acceptors that are methylated on the template strand have the sequence AG (i.e., 790/792 have the template sequence mCT). b, dumpy is a gene with the largest amount of splice junction methylation in both EHB (12 sites) and AHB (4 sites).