Table 2 EMT-related functions
Ontology | Description | Downregulated genes | p value |
|---|---|---|---|
Pathway Commons | Nectin adhesion pathway | CP(↓),DUSP1,DUSP6,EFNA1,FGA(↓),FGB(↓),FOS(↓),GDF15(↓),HES1,IKBKG,NEDD4L(↓),ODC1,PIK3CA, SERPINE1,SMAD3,TGIF1,VTN | 0.0207 |
Pathway Commons | Signaling events mediated by focal adhesion kinase | CP(↓),DUSP1,DUSP6,EFNA1,FGA(↓),FGB(↓),FOS(↓),GDF15(↓),HES1,IKBKG,NEDD4L(↓),ODC1,PIK3CA, SERPINE1,SMAD3,TGIF1,VTN | 0.0207 |
Pathway Commons | FOXA1 transcription factor network | FOS(↓),FOXA2(↓),NR2F2(↓),TFF1,VTN | 0.0319 |
GO Cellular Component | Fibrinogen complex | FGA(↓),FGB(↓),FGL1(↓) | 0.0207 |
GO Biological Process | Cell communication | ANG(↓),DHCR24(↓),DUSP1,DUSP6,ECT2(↓),EFNA1,ELK3,F2RL1,FGA(↓),FGB(↓),FGL1(↓),FOS(↓), FOXA2(↓),FRAT1(↓),FRAT2,GDF15(↓),GLRX2,GPR126,GPRC5A(↓),GUCA1B,HES1,HNF1A,HNF1B, IKBKG,KLF9,MCU(↓),NAB2,NFE2L2(↓),NR1D1,NR2F2(↓),PDK4(↓),PIK3CA,PLA2G1B,PLCD3,PPAP2B, RAPGEF3,RARB,SARM1,SMAD3,UBB,UBC, | 0.0006 |