Table 3 GO enrichment analysis of genes up- or down-regulated in response to AW stress
Tissue | Go term | Definition | No. up- or down- regulated | Total in category | P value |
|---|---|---|---|---|---|
Liver | Up | ||||
GO:0016491 | oxidoreductase activity | 52 | 616 | 0.001 | |
GO:0005215 | transporter activity | 139 | 690 | 0.001 | |
GO:0008047 | enzyme activator activity | 30 | 141 | 0.019 | |
GO:0045182 | translation regulator activity | 1 | 65 | 0.009 | |
GO:0002376 | immune system process | 70 | 219 | 0.001 | |
GO:0008152 | metabolic process | 686 | 5,566 | 0.010 | |
Down | |||||
GO:0016740 | transferase activity | 201 | 1,555 | 0.002 | |
GO:0009055 | electron carrier activity | 28 | 99 | 0.001 | |
GO:0016491 | oxidoreductase activity | 132 | 616 | 0.000 | |
GO:0030234 | enzyme regulator activity | 77 | 506 | 0.001 | |
GO:0009056 | catabolic process | 139 | 1,061 | 0.007 | |
GO:0009058 | biosynthetic process | 216 | 1,791 | 0.027 | |
Kidney | Up | ||||
GO:0016491 | oxidoreductase activity | 150 | 616 | 0.000 | |
GO:0016740 | transferase activity | 165 | 1,555 | 0.000 | |
GO:0016829 | lyase activity | 32 | 121 | 0.000 | |
GO:0005215 | transporter activity | 77 | 690 | 0.005 | |
GO:0009055 | electron carrier activity | 32 | 99 | 0.000 | |
GO:0030234 | enzyme regulator activity | 56 | 506 | 0.001 | |
GO:0050896 | response to stimulus | 91 | 678 | 0.000 | |
Down | |||||
GO:0016491 | oxidoreductase activity | 41 | 616 | 0.000 | |
GO:0005215 | transporter activity | 124 | 690 | 0.000 | |
GO:0030234 | enzyme regulator activity | 93 | 506 | 0.001 | |
GO:0003700 | transcription factor activity | 75 | 488 | 0.042 | |
Gill | Up | ||||
GO:0030528 | transcription regulator activity | 1 | 524 | 0.041 | |
GO:0008152 | metabolic process | 108 | 5,566 | 0.001 | |
GO:0007154 | cell communication | 10 | 1,772 | 0.019 | |
Down | |||||
GO:0050896 | response to stimulus | 26 | 678 | 0.011 | |
GO:0042221 | response to chemical stimulus | 12 | 217 | 0.003 |