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Figure 6 | BMC Genomics

Figure 6

From: Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation

Figure 6

Phylogenetic prediction of future pan- genome growth. Using the same dataset as in Figure 4, the pan-genome sizes (y-axis) were re-plotted against the number of distinct phylogenetic groups (x-axis) these genomes represent, another phylogeny-guided way to linearize the prediction of pan-genome sizes. (A) Each point represents the pan-genome size (y-axis) of a group of randomly selected genomes. The number of distinct B. burgdorferi s.l. species these genomes represent is plotted on x-axis. Based on the linearity of the median values, we estimate that sequencing an additional species would yield ~100 new genes. (B) Each point represents the pan-genome size (y-axis) of a group of randomly selected genomes. The number of distinct B. burgdorferi s.s. SNP groups these genomes represent is plotted on x-axis. Predicted increase of the B. burgdorferi s.s. pan-genome with increasing number of SNP groups. Based on the linear median values, we estimate that sequencing an additional new SNP group (e.g., a European lineage) would yield merely ~10 new genes.

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