Figure 4

Coherence of transcription levels in various metabolic pathways in rapidly growing B. sudeticus cells. (A) Distribution of pathway-associated ESTs based on rank by level. Left panel shows the heat-map of individual EST occurrence based on rank by level. Classes of metabolic pathways are indicated on the far left. Numbers of ESTs associated with the pathway is shown in parentheses. RP stands for ribosomal proteins as control (e.g., C1 or C2). Right panel shows the relative occurrence density in the 3 half-ranges (F for first 50%, M for middle 50%, and S for second 50%) of the pathway-associated ESTs and in the range of top 10% of the most abundant ESTs (i.e., T). Metabolic pathways are numbered on the far right. (B) Coherently transcribed metabolic pathways in rapidly growing B. sudeticus cells. Distribution of metabolic pathway-associated ESTs displaying the enriched level (i.e., 2-fold above background; p-value < 0.05) in one of the 3 half-ranges (F, M, or S) is shown. Level of statistical significance is indicated by triple asterisk (***), double asterisk (**), and single asterisk (*) for p-value < 0.001, 0.01, and 0.05, respectively.