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Table 2 Deregulated miRNA targets in dataset comparing mRNA expression between the cell line and keratinocytes

From: High-throughput sequencing of small RNA transcriptomes reveals critical biological features targeted by microRNAs in cell models used for squamous cell cancer research

Gene target

Up-regulated in cell line

Up-regulated in Keratinocyte

Related miRNA

ADAR

3.6

 

miR-1

ANKRD29

 

4.1

miR-1

ANP32B

3.4

 

miR-1

ATP6V1B2

 

2

miR-1

CDCP1

 

2.3

miR-1

EPB41L4B

 

4.3

miR-1

FSTL1

 

4.7

miR-1

KCNQ1

8

 

miR-1

POLA2

2.9

 

miR-1

PREX1

12

 

miR-1

SSNA1

2.6

 

miR-1

UST

4.6

 

miR-1

CDK9

2.3

 

miR-1

B3GALT4

2.7

 

miR-125

BMF

31

 

miR-125

CDKN2A

 

21

miR-125

IGFBP3

700

 

miR-125

RHOA

 

2.3

miR-133a

SET

2.5

 

miR-196a

SPRR2C

 

71

miR-196a

SNCA

 

5

miR-7

  1. The table reports 21 validated gene targets presenting deregulation between SCC25 and keratinocytes. Fold-change in bold-type indicates that the fold-change is in agreement with the expression level of the regulator miRNA in the cell.