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Table 2 Summary of the enriched GO Biological Process terms in SPATS2L and KLF6 coexpression networks

From: Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis

Biological process in SPATS2L network

   

Term

Count

%

p-value

GO:0051276 ~ chromosome organization

5

12.8

1.90E-02

GO:0042273 ~ ribosomal large subunit biogenesis

2

5.1

2.12E-02

GO:0006461 ~ protein complex assembly

5

12.8

2.17E-02

GO:0070271 ~ protein complex biogenesis

5

12.8

2.17E-02

GO:0042254 ~ ribosome biogenesis

3

7.7

2.79E-02

GO:0034622 ~ cellular macromolecular complex assembly

4

10.3

2.99E-02

GO:0034621 ~ cellular macromolecular complex subunit organization

4

10.3

4.01E-02

GO:0006325 ~ chromatin organization

4

10.3

4.63E-02

Biological process in KLF6 network

   

Term

Count

%

p-value

GO:0006695 ~ cholesterol biosynthetic process

5

6.33

3.95E-06

GO:0016126 ~ sterol biosynthetic process

5

6.33

1.35E-05

GO:0044271 ~ nitrogen compound biosynthetic process

8

10.13

4.08E-04

GO:0006694 ~ steroid biosynthetic process

5

6.33

4.45E-04

GO:0008203 ~ cholesterol metabolic process

5

6.33

6.01E-04

GO:0016125 ~ sterol metabolic process

5

6.33

8.54E-04

GO:0009070 ~ serine family amino acid biosynthetic process

3

3.80

9.36E-04

GO:0008652 ~ cellular amino acid biosynthetic process

4

5.06

1.28E-03

GO:0008610 ~ lipid biosynthetic process

7

8.86

2.30E-03

GO:0008299 ~ isoprenoid biosynthetic process

3

3.80

3.16E-03

GO:0009309 ~ amine biosynthetic process

4

5.06

4.80E-03

GO:0006094 ~ gluconeogenesis

3

3.80

4.92E-03

GO:0009069 ~ serine family amino acid metabolic process

3

3.80

5.31E-03

GO:0019319 ~ hexose biosynthetic process

3

3.80

7.50E-03

GO:0070814 ~ hydrogen sulfide biosynthetic process

2

2.53

8.41E-03

GO:0070813 ~ hydrogen sulfide metabolic process

2

2.53

8.41E-03

GO:0019344 ~ cysteine biosynthetic process

2

2.53

8.41E-03

GO:0034976 ~ response to endoplasmic reticulum stress

3

3.80

8.97E-03

  1. List of enriched GO terms related to biological process (BP) in the SPATS2L (p-value < 0.05) and KLF6 coexpression networks (p-value < 0.01). For each term, the number of genes present in the network (count), the percentage of enrichment (%) and the associated p-value are indicated.