Genome-wide gene expression analysis of anguillid herpesvirus 1

Beurden, Steven J van; Peeters, Ben PH; Rottier, Peter JM; Davison, Andrew J; Engelsma, Marc Y

doi:10.1186/1471-2164-14-83

BMC Genomics

Table 1 Expression of selected AngHV1 genes, sorted on the basis of their R _i-PAA -values at t = 6 hpi

From: Genome-wide gene expression analysis of anguillid herpesvirus 1

ORF^a	Mean^b	STDEV^c	Kinetic class^d	Function^e
1	1.800	0.475	Immediate early
6A	1.059	0.115	Immediate early
127	0.690	0.120	Immediate early
87	0.609	0.019	Early	Serine-threonine protein kinase
39	0.529	0.057	Early	Tegument protein
14*	0.522	0.022	Early	Tegument protein
101	0.519	0.089	Early	Tumour necrosis factor receptor domain
131	0.493	0.016	Immediate early
15*	0.462	0.074	Early	Guanosine triphosphatase
55	0.457	0.004	Early	DNA polymerase
10	0.442	0.156	Early	ATPase subunit of terminase
18*	0.429	0.038	Early/Late	Tegument protein
67	0.427	0.078	Early/Late	Major glycoprotein
66	0.417	0.036	Early/Late	Envelope protein
116	0.359	0.002	Early/Late	Ribonucleotide reductase (large subunit)
123	0.340	0.039	Early/Late	Deoxyguanosine kinase
78	0.329	0.032	Early/Late	Envelope protein
37*	0.316	0.041	Early/Late	DNA helicase
5	0.313	0.064	Early/Late	Deoxyuridine thriphosphatase
108	0.308	0.011	Early/Late	Envelope protein
77*	0.287	0.004	Early/Late	Thymidylate kinase
38	0.271	0.023	Early/Late	Tegument protein
90	0.264	0.007	Early/Late	Nucleoside diphosphate kinase
83	0.263	0.073	Early/Late	Large tegument protein
21	0.262	0.058	Early/Late	Primase
29	0.259	0.025	Early/Late	Uracil-DNA glycosylase
19*	0.253	0.005	Early/Late	Tegument protein
75	0.246	0.034	Early/Late	Thymidylate synthetase
34	0.242	0.028	Late	Tegument protein
125	0.222	0.024	Late	Envelope protein
43*	0.206	0.072	Late	Tegument protein
32*	0.201	0.051	Late	Tegument protein
71	0.199	0.023	Late	Envelope protein
81*	0.196	0.013	Late	Tegument protein
79	0.188	0.027	Late	Deoxyguanosine kinase
40	0.185	0.038	Late	Tegument protein
20*	0.179	0.002	Late	Tegument protein
124*	0.174	0.012	Late	Tumour necrosis factor receptor domain
119	0.170	0.028	Late	Dihydrofolate reductase
17*	0.162	0.020	Late	Tegument protein
100	0.160	0.034	Late	Capsid protein
36*	0.154	0.071	Late	Capsid triplex protein 2
114	0.153	0.025	Late	Tegument protein
26	0.147	0.062	Late	Tegument protein
24	0.145	0.076	Late	Tegument protein
96	0.124	0.029	Late	Ribonucleotide reductase (small subunit)
30	0.110	0.057	Late	Tegument protein
49	0.090	0.013	Late	Envelope protein
16	0.079	0.023	Late	Tegument protein
115	0.070	0.013	Late	Envelope protein
35*	0.068	0.011	Late	Tegument protein
48	0.068	0.015	Late	Capsid protein
57*	0.066	0.022	Late	Capsid protease-and-scaffolding protein
25*	0.063	0.016	Late	Interleukin 10 homolog
51	0.063	0.026	Late	Envelope protein
103	0.057	0.012	Late	Tegument protein
104*	0.050	0.007	Late	Major capsid protein
126	0.031	0.008	Late	Capsid protein
42*	0.024	0.001	Late	Capsid triplex protein 1
8	0.010	0.004	Late	Envelope protein
95	0.010	0.000	Late	Envelope infectious salmon anaemia virus haemagglutinin-esterase protein

^a ORF numbering corresponds to van Beurden et al.[22]; only ORFs for which a putative function has been predicted are shown; ORFs from which the data are potentially compromised by 3’-coterminality are marked with asterisks.
^b Mean R_i-PAA-values were calculated from two independent experiments.
^c Standard deviations of R_i-PAA-values were calculated from two independent experiments.
^d Immediate-early genes were classified on the basis of CHX inhibition experiments; boundaries between early, early-late and late genes are explained in the text.
^e Gene functions were predicted based on similarity with known functional protein sequences [22], and on AngHV1 structural protein analyses by mass spectrometry [29].

Back to article page

ISSN: 1471-2164

Contact us

Submission enquiries: bmcgenomics@biomedcentral.com
General enquiries: ORSupport@springernature.com