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Table 1 Statistically significant KEGG classifications of differentially expressed genes in CYP2S1 depleted cells

From: A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells

KEGG term

Count

%*

P value (EASE score)

Fold enrichment

Cell Cycle

32

1.18

7.96E-04

1.83

Lysosome

29

1.07

2.49E-03

1.77

Apoptosis

22

0.81

7.43E-03

1.80

Prostate cancer

22

0.81

9.73E-03

1.76

Sphingolipid metabolism

12

0.44

1.52E-02

2.19

TGF-beta signaling pathway

21

0.78

1.53E-02

1.72

Nucleotide excision repair

12

0.44

3.62E-02

1.95

Pancreatic cancer

17

0.63

3.77E-02

1.68

N-Glycan biosynthesis

12

0.44

4.86E-02

1.86

mTOR signaling pathway

13

0.48

5.17E-02

1.78

Aminoacyl-tRNA biosynthesis

11

0.41

5.20E-02

1.91

Glycine serine and threonine metabolism

9

0.33

5.85E-02

2.07

Bladder cancer

11

0.41

6.01E-02

1.87

Pathways in cancer

57

2.11

6.03E-02

1.24

Glutathione metabolism

12

0.44

8.14E-02

1.71

Nitrogen metabolism

7

0.26

9.14E-02

2.17

Non-homologous end-joining

5

0.19

9.65E-02

2.74

  1. *Indicates the percentage of genes in each pathway from 2702 genes mapped to KEGG.