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Table 1 Statistically significant KEGG classifications of differentially expressed genes in CYP2S1 depleted cells

From: A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells

KEGG term Count %* P value (EASE score) Fold enrichment
Cell Cycle 32 1.18 7.96E-04 1.83
Lysosome 29 1.07 2.49E-03 1.77
Apoptosis 22 0.81 7.43E-03 1.80
Prostate cancer 22 0.81 9.73E-03 1.76
Sphingolipid metabolism 12 0.44 1.52E-02 2.19
TGF-beta signaling pathway 21 0.78 1.53E-02 1.72
Nucleotide excision repair 12 0.44 3.62E-02 1.95
Pancreatic cancer 17 0.63 3.77E-02 1.68
N-Glycan biosynthesis 12 0.44 4.86E-02 1.86
mTOR signaling pathway 13 0.48 5.17E-02 1.78
Aminoacyl-tRNA biosynthesis 11 0.41 5.20E-02 1.91
Glycine serine and threonine metabolism 9 0.33 5.85E-02 2.07
Bladder cancer 11 0.41 6.01E-02 1.87
Pathways in cancer 57 2.11 6.03E-02 1.24
Glutathione metabolism 12 0.44 8.14E-02 1.71
Nitrogen metabolism 7 0.26 9.14E-02 2.17
Non-homologous end-joining 5 0.19 9.65E-02 2.74
  1. *Indicates the percentage of genes in each pathway from 2702 genes mapped to KEGG.