Figure 2

Cell viability (c.f.u.) of Saccharomyces cerevisiae BY4741 and of 31 isogenic mutant strains tested individually. Cells were exposed to 100 mM acetic acid in YPD medium at pH 3.0, for 100 min. The sag1Δ strain was the only strain whose viability was not statistically different from the wild-type strain. The strains map1Δ, gpm2Δ, nnf2Δ, msr1Δ, iba57Δ and bas1Δ have lower cell viability, while the remaining strains have a higher survival than the wild-type strain. All the results are in accordance with those of the screening. Values represent means and standard deviations of at least 3 independent experiments. Statistical analysis was performed using a one-way ANOVA test. The difference between the wild-type and deletion strains, statistically significant: ***P < 0.0001.