Phylogenetic relationship and virulence inference of Streptococcus Anginosus Group: curated annotation and whole-genome comparative analysis support distinct species designation

Table 4 Unique genes found in SAG strains, as determined by OrthoMCL analysis

Locus name^a	Length (AA)^b	Gene product	% G + C	COG #^c	% HSP^d	PID^e	Organism^f	Accession #
SCRE_0567	128	Conserved hypothetical protein	22.22	3514	108.5	37	S. macacae	ZP_09135394
SCRE_0686*	202	Putative phosphoglycerate mutase	36.95	4151	100.0	50	Paenibacillus sp	YP_003241041
SCRE_1286	126	Conserved hypothetical protein	32.55	4048	100.0	41	Leuconostoc fallax	ZP_08312902
SCRE_1287	278	Conserved hypothetical protein	38.47	4049	100.0	57	Lactobacillus casei	YP_805494
SCRE_1374*	316	Tagatose 1,6-diphosphate aldolase	39.43		100.0	65	Pasterurella mutocida	ZP_18466110
SCRE_1851*	333	Conserved hypothetical protein	38.82	3609	100.6	28	S. gordonii	YP_001449372
SCRE_1887*	229	Triose-phosphate isomerase	28.41	4057	100.0	40	Leuconostoc citreum	YP_001728668
SCRE_1888	179	Conserved hypothetical protein	27.96	3880	100.0	48	Bacillus sp	ZP_01723913

*Genes found in all sequenced SAG from GenBank and this study. ^aS. constellatus subsp. pharyngis C232 was used as reference for all SAG strains; ^bLength of protein within SAG strains in amino acids; ^cCOG number generated during orthoMCL analysis; ^dPercent coverage of protein from SAG compared to best match in NCBI database using BlastP; ^ePID is equal to the percent aa identity for the best match using BlastP from NCBI ; ^fOrganisms with best protein match to a non-SAG strain from NCBI database using BlastP.

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