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Table 1 The power comparisons at different proportions of causal variants

From: A probabilistic method for identifying rare variants underlying complex traits

Total

Causal

RareProb

RareCover

RWAS

LRT

100

50

100%

100%

100%

100%

200

50

100%

100%

99.6%

99.9%

400

50

100%

100%

85.3%

88.6%

600

50

100%

94.6%

54.1%

58.8%

800

50

100%

0.0%

33.0%

36.5%

1000

50

100%

0.0%

20.7%

22.0%

2000

50

100%

0.0%

2.0%

2.0%

3000

50

100%

0.0%

0.8%

0.0%

4000

50

100%

0.0%

0.4%

0.0%

5000

50

100%

0.0%

0.3%

0.0%

200

1*

51.0%

0.0%

0.0%

0.0%

400

3*

77.0%

0.0%

0.0%

0.0%

600

2*

63.6%

0.0%

0.0%

0.0%

800

3*

57.1%

0.0%

0.0%

0.0%

1000

3*

59.0%

0.0%

0.0%

0.0%

2000

1*

34.0%

0.0%

0.0%

0.0%

3000

2*

41.2%

0.0%

0.0%

0.0%

4000

3*

40.0%

0.0%

0.0%

0.0%

5000

2*

29.8%

0.0%

0.0%

0.0%

  1. The upper section of this table shows the results with a fixed number of causal variants. The column "Causal" shows the number of causal variants, and "*" indicates that the value is an average value."