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Table 1 The power comparisons at different proportions of causal variants

From: A probabilistic method for identifying rare variants underlying complex traits

Total Causal RareProb RareCover RWAS LRT
100 50 100% 100% 100% 100%
200 50 100% 100% 99.6% 99.9%
400 50 100% 100% 85.3% 88.6%
600 50 100% 94.6% 54.1% 58.8%
800 50 100% 0.0% 33.0% 36.5%
1000 50 100% 0.0% 20.7% 22.0%
2000 50 100% 0.0% 2.0% 2.0%
3000 50 100% 0.0% 0.8% 0.0%
4000 50 100% 0.0% 0.4% 0.0%
5000 50 100% 0.0% 0.3% 0.0%
200 1* 51.0% 0.0% 0.0% 0.0%
400 3* 77.0% 0.0% 0.0% 0.0%
600 2* 63.6% 0.0% 0.0% 0.0%
800 3* 57.1% 0.0% 0.0% 0.0%
1000 3* 59.0% 0.0% 0.0% 0.0%
2000 1* 34.0% 0.0% 0.0% 0.0%
3000 2* 41.2% 0.0% 0.0% 0.0%
4000 3* 40.0% 0.0% 0.0% 0.0%
5000 2* 29.8% 0.0% 0.0% 0.0%
  1. The upper section of this table shows the results with a fixed number of causal variants. The column "Causal" shows the number of causal variants, and "*" indicates that the value is an average value."