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Table 2 The power comparisons for different configurations of regions

From: A probabilistic method for identifying rare variants underlying complex traits

Total

Causal

Regions

Length

RareProb

Correct R

1000

36*

1

50

100%

96%

 

37*

2

50

100%

98%

 

36*

3

50

100%

97%

 

35*

4

50

100%

98%

2000

73*

1

100

100%

97%

 

73*

2

100

100%

97%

 

70*

3

100

100%

98%

 

71*

4

100

100%

96%

Total

Causal

Regions

Length

RareCover

Correct R

1000

36*

1

50

0.0%

1.9%

 

37*

2

50

0.0%

1.4%

 

36*

3

50

0.0%

1.7%

 

35*

4

50

0.0%

1.6%

2000

73*

1

100

0.0%

0.7%

 

73*

2

100

0.0%

0.8%

 

70*

3

100

0.0%

1.3%

 

71*

4

100

0.0%

0.8%

  1. The column "Causal" represents the total number of causal variants, "Region" denotes the total number of elevated regions, "Length" indicates the total number of variants locating in elevated regions. The column "Correct R" shows the percentage of correct identification of regions.