Figure 3
From: FitSearch: a robust way to interpret a yeast fitness profile in terms of drug's mode-of-action
Plot of an overlapping score and an overlapping significance as two-way cutoffs to show the most similar chemical or genetic effects to a query's effect. (A) Two-way cutoff plot of the most similar chemical effects to the 5-Fluorouracil's effect. (B) Two-way cutoff plot of similar chemical effects to clotrimazole's effect. (C) Two-way cutoff plot of the most similar genetic effects to clotrimazole's effect. (D) Two-way cutoff plot of the most similar chemical effects to DAPG's effect. Target sources mean public chemical-genetic or genetic-genetic yeast profiles.