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Table 1 Dataset composition.

From: Identifying Mendelian disease genes with the Variant Effect Scoring Tool

Class Training set Benchmark test set Benchmark training set
Disease 47724 32841 14883
Neutral 45818 31018 14800
  1. The VEST training set comprises a balanced number of disease-causing and neutral missense mutations. In order to compare VEST performance to other methods, the VEST training set was divided into a benchmark test set for evaluating methods, and a benchmark training set, used for training a VEST classifier for unbiased comparison.