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Figure 4 | BMC Genomics

Figure 4

From: Revealing selection in cancer using the predicted functional impact of cancer mutations. Application to nomination of cancer drivers

Figure 4

The percentages of potential "passenger" genes predicted within genes sets presented in the histograms of Figure 3. Potential "passengers" genes are defined as genes that have more or equal number of low functional mutations (FIS<1.0) as compared to a number of high-functional mutations, i.e. missense mutations of FIS>2.5 and truncating mutations; "MM+TM" refers to genes affected by either missense (MM) or truncating (TM) mutations; CanGenes referes to "cancer genes".

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