Sequence and structure based models of HIV-1 protease and reverse transcriptase drug resistance

BMC Genomics

Table 5 Predictive accuracy of REPTree and RF using relative frequency and counts methods to represent dataset sequences

	Relative Frequency		Counts
Drug	REPTree	RF	REPTree	RF	Drug Mean
Protease Inhibitors
APV	0.81	0.80	0.80	0.80	0.80
ATV	0.74	0.75	0.76	0.76	0.75
IDV	0.78	0.80	0.75	0.80	0.78
LPV	0.80	0.82	0.80	0.81	0.81
NFV	0.80	0.80	0.79	0.82	0.80
RTV	0.87	0.86	0.87	0.84	0.86
SQV	0.80	0.79	0.80	0.80	0.80
TPV	0.75	0.79	0.75	0.81	0.78
AVG	0.79	0.80	0.79	0.81	0.80
Nucleoside/Nucleotide RT Inhibitors
3TC	0.89	0.87	0.87	0.90	0.88
ABC	0.68	0.68	0.66	0.67	0.67
AZT	0.75	0.75	0.73	0.70	0.73
d4T	0.74	0.79	0.76	0.78	0.77
ddC	0.80	0.75	0.80	0.76	0.78
ddI	0.69	0.73	0.69	0.71	0.71
FTC	0.96	0.83	0.94	0.89	0.91
TDF	0.75	0.75	0.68	0.74	0.73
AVG	0.78	0.77	0.77	0.77	0.77
Nonnucleoside RT Inhibitors
DLV	0.76	0.70	0.76	0.71	0.73
EFV	0.78	0.74	0.76	0.73	0.75
NVP	0.84	0.79	0.82	0.77	0.81
AVG	0.79	0.74	0.78	0.74	0.76

ISSN: 1471-2164