From: Post genome-wide association studies functional characterization of prostate cancer risk loci
GO terms | Observed* | p-value# |
---|---|---|
GO Biological Processes | Â | Â |
Regulation of cell death | 40 | 4.944 × 10-9 |
Regulation of apoptosis | 39 | 5.506 × 10-9 |
Regulation of programmed cell death | 39 | 6.945 × 10-9 |
Response to external stimulus | 39 | 1.237 × 10-8 |
Metabolic process | 133 | 2.357 × 10-8 |
Epithelial cell proliferation | 9 | 7.699 × 10-8 |
Response to organic cyclic compound | 19 | 1.153 × 10-7 |
Negative regulation of biological process | 61 | 1.650 × 10-7 |
Rhythmic process | 15 | 2.056 × 10-7 |
Branching morphogenesis of a tube | 12 | 2.070 × 10-7 |
GO Molecular Functions | Â | Â |
Insulin-like growth factor receptor binding | 11 | 6.617 × 10-18 |
Insulin receptor binding | 10 | 1.501 × 10-12 |
Protease binding | 11 | 1.685 × 10-11 |
Binding | 156 | 1.574 × 10-10 |
Protein binding | 115 | 1.593 × 10-9 |
Protein complex binding | 17 | 2.310 × 10-7 |
Hormone activity | 10 | 4.671 × 10-6 |
Catalytic activity | 76 | 3.102 × 10-5 |
Oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor | 5 | 6.596 × 10-5 |
4 iron, 4 sulfur cluster binding | 4 | 8.215 × 10-5 |
GO Localizations | Â | Â |
Cytoplasmic part | 99 | 1.009 × 10-6 |
Mitochondrial envelope | 19 | 2.992 × 10-6 |
Mitochondrial part | 22 | 9.733 × 10-6 |
Envelope | 23 | 1.480 × 10-5 |
Mitochondrion | 34 | 2.505 × 10-5 |
Organelle envelope | 22 | 3.432 × 10-5 |
Mitochondrial inner membrane | 13 | 7.758 × 10-5 |
Mitochondrial respiratory chain complex I | 5 | 7.937 × 10-5 |
NADH dehydrogenase complex | 5 | 7.937 × 10-5 |
Respiratory chain complex I | 5 | 7.937 × 10-5 |