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Table 1 The group of calcium signaling-associated genes screened from microarrays

From: Substrate-dependent gene regulation of self-assembled human MSC spheroids on chitosan membranes

Gene symbol

Gene full name

Ratio (MA)

Ratio (qRT-PCR)

ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

2.40

3.17 ± 0.88*

ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

0.48

0.68 ± 0.23*

SLC8A1

solute carrier family 8 (sodium/calcium exchanger), member 1

0.22

0.40 ± 0.15*

TRPA1

transient receptor potential cation channel, subfamily A, member 1

4.46

24.58 ± 16.15*

TRPC4

transient receptor potential cation channel, subfamily C, member 4

0.21

0.02 ± 0.01*

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

10.36

26.92 ± 10.07*

HTR7

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

2.99

-

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

3.29

3.38 ± 1.17*

GPR68

G protein-coupled receptor 68

4.33

10.80 ± 1.42*

F2R

coagulation factor II (thrombin) receptor

2.26

6.98 ± 1.53*

BDKRB2

bradykinin receptor B2

2.59

-

EDNRA

endothelin receptor type A

2.27

-

ADRB2

adrenoceptor beta 2, surface

0.35

-

MAP3K8

mitogen-activated protein kinase kinase kinase 8

3.61

13.31 ± 2.04*

ITPR1

inositol 1,4,5-trisphosphate receptor, type 1

2.23

2.36 ± 0.32*

PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

5.51

6.44 ± 2.70*

RASGRP3

RAS guanyl releasing protein 3 (calcium and DAG-regulated)

4.35

2.78 ± 0.90*

CALM2

calmodulin 2 (phosphorylase kinase, delta)

0.30

0.08 ± 0.05*

  1. MA: based on microarray data.
  2. qRT-PCR: based on quantitative RT-PCR analysis.
  3. *P < 0.05 between CS and TCPS groups (n = 5).