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Table 2 Overview of enrichment analyses of the five identified PrCa modules

From: Key regulators in prostate cancer identified by co-expression module analysis

Module ID      cis-eQTL trans-eQTL SCNA Somatic mutation Prognostic genes
  Description p cor a Size Z summary # genes p cis-eQTL a # genes p trans-eQTL a # genes p SCNA a # genes p mutation a # genes p prog a
M1 Regulation of apoptosis (red) 6.23 × 10−8 29 10.0 17 3.66 × 10−3 13 1.01 × 10−3 NA NA 3 1.99 × 10−4 NA NA
Apoptosis go (black)
M2 Regulation of apoptosis (green) 1.51 × 10−2 26 6.1 15 8.93 × 10−3 7 0.11 2 0.040 NA NA 2 0.081
M3 Response to stress (green) 4.18 × 10−11 37 8.3 19 0.017 14 3.16 × 10−3 NA NA 2 1.37 × 10−3 NA NA
M4 Cellular localization (turquoise) 3.27 × 10−9 70 5.7 35 7.30 × 10−3 9 0.85 6 0.024 NA NA 10 1.62 × 10−3
M5 Protein localization (brown) 8.04 × 10−10 24 5.2 13 0.034 5 0.29 2 0.039 2 6.84 × 10−4 NA NA
  1. ap values were adjusted by FDR method.