Table 2 Overview of enrichment analyses of the five identified PrCa modules
From: Key regulators in prostate cancer identified by co-expression module analysis
Module ID | Â | Â | Â | Â | cis-eQTL | trans-eQTL | SCNA | Somatic mutation | Prognostic genes | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Description | p cor a | Size | Z summary | # genes | p cis-eQTL a | # genes | p trans-eQTL a | # genes | p SCNA a | # genes | p mutation a | # genes | p prog a |
M1 | Regulation of apoptosis (red) | 6.23 × 10−8 | 29 | 10.0 | 17 | 3.66 × 10−3 | 13 | 1.01 × 10−3 | NA | NA | 3 | 1.99 × 10−4 | NA | NA |
Apoptosis go (black) | ||||||||||||||
M2 | Regulation of apoptosis (green) | 1.51 × 10−2 | 26 | 6.1 | 15 | 8.93 × 10−3 | 7 | 0.11 | 2 | 0.040 | NA | NA | 2 | 0.081 |
M3 | Response to stress (green) | 4.18 × 10−11 | 37 | 8.3 | 19 | 0.017 | 14 | 3.16 × 10−3 | NA | NA | 2 | 1.37 × 10−3 | NA | NA |
M4 | Cellular localization (turquoise) | 3.27 × 10−9 | 70 | 5.7 | 35 | 7.30 × 10−3 | 9 | 0.85 | 6 | 0.024 | NA | NA | 10 | 1.62 × 10−3 |
M5 | Protein localization (brown) | 8.04 × 10−10 | 24 | 5.2 | 13 | 0.034 | 5 | 0.29 | 2 | 0.039 | 2 | 6.84 × 10−4 | NA | NA |