Table 2 Mutations identified by whole-exome sequencing
(SnpEff§) High | Moderate | Low | Modifier | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Clone name | Responsible genes* | Total no. of mutations | Nonsense mutations | Splice site alterations | Frameshift mutations | Loss of start codon | Nonsynonymous mutations etc.|| | Synonymous mutations | Others¶ | |
B3-1 | Pigt | 220 | 6 | 5 | 0 | 0 | 115 | 39 | 1 | 54 |
B5-1 | Dpm1 | 297 | 6 | 3 | 0 | 1 | 128 | 60 | 2 | 97 |
B7-2 | Pigo | 218 | 5 | 1 | 0 | 0 | 103 | 38 | 1 | 70 |
B102 | Pigb | 10 | 0 | 0 | 1 | 0 | 4 | 0 | 0 | 5 |
B201 | Pigk† | 41 | 1 | 1 | 0 | 0 | 14 | 7 | 0 | 18 |
B502 | Dpm1, Pigv | 511 | 13 | 12 | 1 | 1 | 241 | 110 | 5 | 128 |
B1001 | Pigv | 306 | 8 | 2 | 0 | 0 | 127 | 55 | 1 | 113 |
B1002 | Pigs | 330 | 10 | 2 | 1 | 0 | 152 | 63 | 0 | 102 |
B1007 | Gpaa1 | 23 | 1 | 1 | 0 | 0 | 9 | 2 | 1 | 9 |
F-43 | Pigo‡ | 375 | 12 | 4 | 2 | 0 | 153 | 83 | 2 | 119 |
Average | 233.1 | 10 | 104.6 | 47 | 71.5 | |||||