Figure 5

Case where additional read continuation across a breakpoint is required to support a junction candidate. In certain cases a read alignment must extend further across a junction breakpoint than just through the alignment overlap or read-only sequences to support the junction versus aligning equally well to the original reference sequence. One such case, where there is a deletion of four bases in a short tandem repeat region is shown. In this example, read alignments to the junction candidate sequence must extend across the four overlapping junction bases and the three bases shown on their left side to support the junction.