Figure 2

Clustering of p63 targets by chromatin intensity and shape. p63 bound locations are clustered by 5 active (H3K4me1, H3K4me2, H3K4me3, H3K9ac, H3K27ac) and 2 repressive (H3K9me3, H3K27me3) histone modifications sequenced in NHEK (Normal Human Epidermal Keratinocytes) cell-line. They are first clustered by average signal intensity across a 1 kb window centered at p63 binding site and then clustered by spatial arrangement of the histone modifications.