Averaged k-mer distribution for DGRP flies grouped by repeat class. K-mer frequencies were computed for each sequencing experiment. K-mers were split into quintiles by frequency, with quintile 5 being the most frequent. Each k-mer in the quintile was classified as mapping to short repeat, 359 bp repeat, transposon, and genome assembly or unmapped classes. The median number of k-mers that belonged to each of the repeat classes or that were unmapped for the 10 fly lines is plotted in each quintile. Numbers above indicate the percentage of the total number of k-mers falling into each quintile.