Figure 5

Differentially expressed genes and proteins and KEGG pathway enrichment analysis at 24 hours. Proteins were mapped to gene probes to compare differentially expressed proteins and genes in the heart. Insets show the results of the KEGG pathway enrichment analysis for concordant gene and protein up- and down-regulation. Genes and proteins with the greatest concordance with the pathway enrichment analysis are depicted. Proteins expressed at ±1.3-fold and their respective genes (±2-fold) are represented by red squares. Proteins and genes which mapped together but did not meet significance at the gene level are represented as blue diamonds. Genes (green triangles) or proteins (purple triangles) that were expressed and significant, but did not map together, are plotted along the axes. For clarity, only the gene designations are listed.